NW-oriented features on both sides of the Atlantic Ocean: evidence for a Paleozoic collision that formed the Labrador-Biscay wrench fault zone?

Northwest-oriented features have been recognized for many years as fundamental components of the geology of the northwestern European continental shelves. Similarly oriented lineations and faults have been mapped throughout southwestern Britain, western France and across the English Channel. On land in Europe, similar trends are identified as far east as the Urals. Features of similar orientation, extending over a broad area on the North American continental shelf, have recently been identified from geophysical trends. On land in eastern Canada NW-SE faults have been mapped geologically and detected using geophysical and remote sensing data. A Mercator projection map on which the Atlantic Ocean has been restored to its pre-Mesozoic configuration, i.e. before the initiation of the most recent opening of the North Atlantic Ocean, shows that the features are similarly oriented. Although some of the trends showing this direction may be younger, the geological data from both sides of the Atlantic Ocean suggest that the event that led to the formation of these NW-SE features post-dated the Variscan orogeny and may have been associated with the collision between Gondwana and Laurasia. The geometric patterns of the features interpreted as associated with the collision are consistent with patterns produced by a simple physical sandbox model of indentation with a rigid confinement to the west and a small lateral confinement to the east. This configuration is similar to that expected of Gondwana and Laurasia during the late Paleozoic. Faults considered younger than this collision may represent tectonic rejuvenations associated with the initiation of the opening of the North Atlantic Ocean. RÉSUMÉ L'orientation obscrvée du nord-est vers le sud-est des formations rocheuses est reconnue depuis de nombreuses années comme une caractéristique géologique fondamentale des plateaux continentaux du nord-ouest de l'Europe. Des structures linéaires et des failles d'orientation similaires ont été répertoriées dans tout le sud-ouest de l'Angleterre, dans I'ouest de la France et à travers la Manche. Sur le continent européen, des tendances analogues ont pu fitre observées aussi loin à l'est que dans la chaine de l''Oural. Ces caractérstiques orientées qui recouvrent une vaste région du plateau continental de l'Amerique du Nord ont récemment été observées à partir de tendances géophysiques. Dans l'Est canadien, des failles orientées NO-SE ont été portées sur des cartes géologiques et déectées a l'aid.e de données géophysiques et de télélédétection. Ces caractéristiques observées ont été portées sur une carte a projection de Mercator oò figure l'océan Atlantique dans sa configuration d'origine pendant l'ère pré-mésozoTque, soit avant que ne s'amorce rouverture la plus récente de l'Atlantique Nord. Ces caractéristiques nsproduisent la même orientation lorsqu'elles sont portées ainsi sur la carte. Bien que certaines des tendances qui signalent cette orientation semblent d'apparition plus récente, les données géologiques des deux côtés de l'Atlantique portent à croire que le phénomène qui a mené la création de ces linéations NO-SE est survenu après l'orogenése de varisque et peut fltre relié à l'hypercollision survenue entre la Gondwanie et la Laurasie. Les formes géomètriques de ces linéations interprétées en relation avec la collision sont du même type que eel les produites dans un modèle d'échancrure géologique dans un simple carré de sable, celles-ci présentant un confinement rigide è l'ouest et un petit confinement latéral è Test. Il s'agit d'une configuration semblable à celle qui serait caractéristique de la Gondwanie et de la Laurasie. Les failles jugés plus récentes et issues de cette collision pourraient être attribuables à une régénération tectonique qui a accompagné le début de rouverture de l'Atlantique Nord. Traduit par la rédactio

Tracking the phase-transition energy in disassembly of hot nuclei

In efforts to determine phase transitions in the disintegration of highly excited heavy nuclei, a popular practice is to parametrise the yields of isotopes as a function of temperature in the form $Y(z)=z^{-\tau}f(z^{\sigma}(T-T_0))$, where $Y(z)$'s are the measured yields and $\tau, \sigma$ and $T_0$ are fitted to the yields. Here $T_0$ would be interpreted as the phase transition temperature. For finite systems such as those obtained in nuclear collisions, this parametrisation is only approximate and hence allows for extraction of $T_0$ in more than one way. In this work we look in detail at how values of $T_0$ differ, depending on methods of extraction. It should be mentioned that for finite systems, this approximate parametrisation works not only at the critical point, but also for first order phase transitions (at least in some models). Thus the approximate fit is no guarantee that one is seeing a critical phenomenon. A different but more conventional search for the nuclear phase transition would look for a maximum in the specific heat as a function of temperature $T_2$. In this case $T_2$ is interpreted as the phase transition temperature. Ideally $T_0$ and $T_2$ would coincide. We invesigate this possibility, both in theory and from the ISiS data, performing both canonical ($T$) and microcanonical ($e=E^*/A$) calculations. Although more than one value of $T_0$ can be extracted from the approximate parmetrisation, the work here points to the best value from among the choices. Several interesting results, seen in theoretical calculations, are borne out in experiment.Comment: Revtex, 10 pages including 8 figures and 2 table

Education at the Margins of the Political

This paper argues that the political can respond to that which exceeds it without reducing it to the same, and that public education is one of the most important places where this can happen. I present a rationale for public education to assist that which exceeds the political: singularity, solitude and difference. What I maintain is that the political must welcome this excess, especially through public education, or else it would not be possible to provide the educational context for that which might be of significance to individuals without having socio-political value

Multi-wavelength, all-solid-state, continuous wave mode locked picosecond Raman laser

We demonstrate the operation of a cascaded continuous wave (CW) mode-locked Raman oscillator. The output pulses were compressed from 28 ps at 532 nm down to 6.5 ps at 559 nm (first Stokes) and 5.5 ps at 589 nm (second Stokes). The maximum output was 2.5 W at 559 nm and 1.4 W at 589 nm with slope efficiencies up to 52%. This technique allows simple and efficient generation of short-pulse radiation to the cascaded Stokes wavelengths, extending the mode-locked operation of Raman lasers to a wider range of visible wavelengths between 500 - 650 nm based on standard inexpensive picosecond Nd:YAG oscillators

The retinoid-related orphan receptor RORα promotes keratinocyte differentiation via FOXN1.

RORα is a retinoid-related orphan nuclear receptor that regulates inflammation, lipid metabolism, and cellular differentiation of several non-epithelial tissues. In spite of its high expression in skin epithelium, its functions in this tissue remain unclear. Using gain- and loss-of-function approaches to alter RORα gene expression in human keratinocytes (HKCs), we have found that this transcription factor functions as a regulator of epidermal differentiation. Among the 4 RORα isoforms, RORα4 is prominently expressed by keratinocytes in a manner that increases with differentiation. In contrast, RORα levels are significantly lower in skin squamous cell carcinoma tumors (SCCs) and cell lines. Increasing the levels of RORα4 in HKCs enhanced the expression of structural proteins associated with early and late differentiation, as well as genes involved in lipid barrier formation. Gene silencing of RORα impaired the ability of keratinocytes to differentiate in an in vivo epidermal cyst model. The pro-differentiation function of RORα is mediated at least in part by FOXN1, a well-known pro-differentiation transcription factor that we establish as a novel direct target of RORα in keratinocytes. Our results point to RORα as a novel node in the keratinocyte differentiation network and further suggest that the identification of RORα ligands may prove useful for treating skin disorders that are associated with abnormal keratinocyte differentiation, including cancer

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Graphic Classes in the Worldwide Classroom: A Comparison of Two MOOC Experiences

Graphics are present in the day-to-day professional practice of architects and engineers, not only to receive and transmit information, but also to design and create. Students who are accepted on university courses have varied curriculum vitae, and some may initially lack skills. Consequently, engineering schools have developed a Massive Open Online Course (MOOC) entitled “The Language of Engineering” (ELI), which reviews basic geometry concepts and develops spatial intelligence, among others. The Barcelona School of Architecture has produced “From reality to design. From design to augmented reality” (RA), which covers topics including traditional architectural representation and the latest techniques. The goal of this study was to explain and analyse the main characteristics and learning strategies of these two MOOC (strengths, weaknesses and opportunities for improvement). The results show that although strategies vary depending on the subjects, the contents and exercises should be practical and adapted to students (interests, level, time availability and aesthetics), always considering motivation as a key point (gamification). These topics have been found to have a considerable influence on the success of a MOOC. Therefore, the conclusions should be considered in subsequent versions of these courses and other MOOCs.Postprint (author's final draft